Phytochemical Study, Evaluation of Antihelminthic Potential and In silico Screening for Breast Cancer Using Mimosa pudica Linn.

Velmurugan, Aravinth and Chandramohan, Keerthana and Thamizhselvan, Ganeshan and Shokkalingam, Yogesh and Natarajan, Venkatesan and Devarasu, Pradeepraj and Sendhamaraikannan, Thamizh (2024) Phytochemical Study, Evaluation of Antihelminthic Potential and In silico Screening for Breast Cancer Using Mimosa pudica Linn. Journal of Pharmaceutical Research International, 36 (6). pp. 135-143. ISSN 2456-9119

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Abstract

Breast Cancer is a major health concern in India, where it is highly lethal for women because of unchecked cell proliferation and metastasis, which are frequently caused by interactions between the Estrogen Receptor Alpha and other receptors. Even though they work well, synthetic Anthelmintics come with dangers to the health of both humans and animals. Therefore, creating effective and safe Anthelmintics from plant sources is our main goal. We extracted Mimosa pudica leaves with ethanol using a Soxhlet system, and after concentration, we examined the extract using GC-MS, FTIR, and UV techniques. Estrogen Receptor structure and flavonoid compound databases from PubChem and Protein Data Bank were used for in silico testing against Breast Cancer and anthelmintic action, respectively. Using molecular docking and drug similarity investigations, the effectiveness of natural compounds against Breast Cancer was evaluated.

Item Type: Article
Subjects: East Asian Archive > Medical Science
Depositing User: Unnamed user with email support@eastasianarchive.com
Date Deposited: 13 May 2024 06:35
Last Modified: 13 May 2024 06:35
URI: http://library.eprintdigipress.com/id/eprint/1332

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