Coinfection Tuberculosis and Borreliosis: A Granulomatosis Etiology

Uveitis is an intraocular inflammation that specifically affects the uvea. The granulomatous nature is defined by large inflammatory cell precipitates on the corneal endothelial tissue, inflammatory nodules located at the edge of the pupil, or within the iris stroma. The etiologies are as variable as they are diverse, making diagnosis difficult; they can be idiopathic or secondary to autoimmune conditions such as Vogt-Koyanagi-Harada disease or multiple sclerosis secondary to an inflammatory disease such as sarcoidosis, or to an infectious disease such as tuberculosis or Lyme disease, and sometimes secondary to the overlap of two conditions, one potentially masking the other. This article reports the case of a patient who presented with bilateral granulomatous panuveitis and for whom the etiological workup revealed two associated granulomatous conditions: tuberculosis and borreliosis.